Micah Abbey Donatello (voice) Shamon Brown Jr. Michelangelo (voice) Nicolas Cantu Leonardo (voice) Brady Noon Raphael (voice) Ayo Edebiri April O'Neil (voice) Maya Rudolph Cynthia Utrom (voice) John Cena Rocksteady (voice) Seth Rogen Bebop (voice) Rose Byrne Leatherhead (voice) Natasia Demetriou Wingnut (voice) Giancarlo Esposito Baxter Stockman (voice) Jackie Chan Splinter (voice) Ice Cube Superfly (voice) Paul Rudd Mondo Gecko (voice) Post Malone Ray Fillet (voice) Hannibal Buress Genghis Frog (voice) Jimmy Donaldson Times Square Guy (voice) Derek Wilson Spider (voice) Michael Badalucco Bad Bernie (voice) Dempsey Pappion Bald Bronson (voice) John Capodice Cab Driver (voice) Raechel Wong News Anchor (voice) David Faustino Normal Nate (voice) Danny Mastrogiorgio Toupee Tom / Police Officer (voice) Kevin Eastman Good Human (voice) Alex Hirsch Bossy Goon / Scumbug (voice) Mike Rianda Paycheck Goon / Chop Shop Boss / Ratatouille Guard (voice) Greg Levitan Gecko Goon (voice) Natalie Canizares Sign My Baby Mom (voice) Kyler Spears Apologetic Goon (voice)