Steve Carell Gru (voice) Kristen Wiig Lucy (voice) Will Ferrell Maxime (voice) Sofía Vergara Valentina (voice) Miranda Cosgrove Margo (voice) Dana Gaier Edith (voice) Madison Polan Agnes (voice) Pierre Coffin Minions (voice) Chris Renaud Principal Übelschlecht (voice) Steve Coogan Silas (voice) Stephen Colbert Perry Prescott (voice) Chloe Fineman Patsy Prescott (voice) Joey King Poppy Prescott (voice) Laraine Newman Melora / Additional Voices (voice) John DiMaggio Bus Driver (voice) Tara Strong Additional Voices (voice) Romesh Ranganathan Additional Voices (voice) Brad Ableson Additional Voices (voice) Barbara Harris Additional Voices (voice) JP Karliak Additional Voices (voice) Cathy Cavadini Additional Voices (voice) Arif S. Kinchen Additional Voices (voice) Will Collyer Additional Voices (voice) Jeremy Maxwell Additional Voices (voice) Abby Craden Additional Voices (voice) Ken Daurio Additional Voices (voice) Khary Payton Additional Voices (voice) John DeMita Additional Voices (voice) Aaron Fors Additional Voices (voice) Isaac Robinson-Smith Additional Voices (voice) Willow Geer Additional Voices (voice) Nisa Ward Additional Voices (voice) Aaron Hendry Additional Voices (voice) Colette Whitaker Additional Voices (voice)